Epoxides are three-membered cyclic ethers created in the metabolism of foreign substances and as endogenous metabolites. Epoxide hydrolases (EHs) are enzymes which catalyze the hydrolysis of epoxides to yield the related diols. EHs have been implicated in diverse functions like detoxification of
Anandamide (AEA) is surely an endogenous fatty acid that triggers the same cannabinoid receptors as tetrahydrocannabinol, the psychoactive substance in marijuana. In vivo, anandamide exerts numerous actions including effects upon inflammation and pain. Nevertheless, AEA has a brief time period of action
In the pentose phosphate pathway, carbohydrates such as glucose and ribose are degraded with production of reductive power and energy. Another important function is to produce essential pentoses, such as ribose 5-phosphate, which later can be used in biosynthesis of nucleic acids
During brain activity neurons release the major excitatory transmitter glutamate, which is taken up by astrocytes and converted to glutamine. Glutamine returns to neurons for re-conversion to glutamate. This glutamate-glutamine cycle is energy demanding. Glutamate turnover in injured brain was studied using
Anthocyanins are polyphenolics responsible for most red to purple colors in plants. Human consumption is increasing because of their potential health benefits and use as natural colorants. However, their absorption and metabolism are not well characterized. We compared anthocyanin absorption and excretion