human islets Archives - Projects, Thesis, Dissertation, Project Reports

Role of Islet Endothelial Cells in β-cell Function and Growth

The pancreatic islets are collections of endocrine cells, spread through the pancreas. In adult islets, endocrine cells are tightly related to capillary endothelial cells and get a high blood perfusion. Transplanted pancreatic islets, on the contrary, have a vascular disturbance, manifested as

Inflammatory Mediators and Enterovirus Infections in Human Islets of Langerhans

Type 1 diabetes (T1D) is due to a selective loss of the insulin producing β-cells. However, the process responsible for this loss is still unknown. There is accumulating evidence that enteroviruses (EVs) are involved in T1D. In addition to direct virus-induced cytolysis,

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