An elevated chance for coronary heart disease among shift employees is previously revealed in the epidemiological literature. The purpose of this dissertation is to penetrate metabolic disturbances and weight problems amongst shift employees when compared with day employees, and to evaluate if there are variations in overall mortality or trigger particular fatality of coronary heart disease (CHD), diabetes or ischaemic stroke among the 2 groups. In an intervention research on women nurses (N=11), on night schedules in Umeå hospital, the biggest peak value of glucose and insulin following meal ingestion had been observed in the late night (23:30). The post-prandial area under curve (AUC) of glucose and insulin was correspondingly biggest following food intake the same clock hour when compared with food intake other clock times…
Contents
NTRODUCTION
BACKGROUND
SHIFT WORK
HEALTH ISSUES IN A 24/ 7 SOCIETY
PRESENT GUIDELINES AND RECOMMENDATIONS GOVERNING
MEDICAL SURVEILLANCE OF SHIFT WORKERS.
HEALTH EFFECTS OF SHIFT WORK
Accidents
Sleep problems
Gastrointestinal disease
Pregnancy
Cancer
Cardiovascular disease (CVD)
General Mortality and Cause-Specific Mortality
METABOLIC EFFECTS OF SHIFT WORK
“Normal physiology in short” with focus on plasma lipids,
the metabolic syndrome, impaired glucose tolerance (IGT),
obesity and diabetes
Circadian rhythmicity in the human body
Specific rhythmicity of biomarkers such as glucose,
corresponding insulin secretion and lipids
Shift related dietary intake and energy expenditure in day and shift workers.
PUBLISHED EPIDEMIOLOGICAL RESEARCH INTO METABOLIC
RISK FACTORS IN SHIFT WORKERS
Triglycerides, Total cholesterol and HDL-cholesterol
Fibrinolytic activity, fasting glucose, HBA1c, insulin,
type-II diabetes, as isolated biomarkers or in combination
Measurements of obesity and the metabolic syndrome
Hypertension and cardiac rhythm
Homocysteine
MECHANISMS OF SELECTION
Selection in the general population
Selection in day and shift work
THE AIMS OF THE THESIS…
Metabolic disturbances in shift workers downloads
Source: Umea University
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