The endothelium plays an important part in blood flow regulation by producing the vasodilatory substance nitric oxide (NO). Various studies have shown that commonly accepted risk factors for coronary heart disease, such as hypertension, diabetes, hypercholesterolemia, smoking and mental stress impair endothelium-derived vasodilation by the NO-pathway. This thesis focuses on the effects of mental stress on the endothelium…
Contents
INTRODUCTION
BACKGROUND
MENTAL STRESS AND CARDIOVASCULAR DISEASES
MENTAL STRESS
COLD PRESSOR TEST
THE ENDOTHELIUM
MENTAL STRESS AND EDV
AIMS OF THE STUDIES
METHODS
SUBJECTS
STUDY PROTOCOLS
VENOUS OCCLUSION PLETHYSMOGRAPHY (STUDIES I-III)
EVALUATION OF EDV AND EIDV (STUDIES I-III)
ENDOTHELIAL FUNCTION INDEX (STUDIES I-II)
BLOCKADES (STUDIES I-II
PLASMA CATECHOLAMINE MEASUREMENTS (STUDY III)
THE BRACHIAL ARTERY ULTRASOUND TECHNIQUE (STUDY IV)
STRESS TESTS (STUDIES II AND IV)
HEMODYNAMIC MONITORING
STATISTICAL ANALYSIS
RESULTS AND DISCUSSION
STUDY I…
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Author: Johansson, Kristina
Source: Uppsala University Library
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