Our knowledge of the fine structure of the Human Spiral Ganglion (HSG) is still inadequate and new treatment techniques for deafness using electric stimulation, call for further information and studies on the neuronal elements of the human cochlea. This thesis presents results of analyses of human cochlear tissue and specimens obtained during neurosurgical transpetrosal removal of life-threatening meningeomas…
Contents
INTRODUCTION
Presentation
History
Cochlear anatomy
Cochlear physiology
Cochlear innervation
The sensory auditory systems
The spiral ganglion
Specific characteristics of the human spiral ganglion
Tight and gap junctions
OBJECTIVES OF THE STUDIES
MATERIAL AND METHODS
RESULTS
Preservation
Light microscopic studies and TEM studies in papers I, II, and III
TEM study, paper IV
Study on synaptophysin immunoreactivity, paper III
Studies on immunoreactivity of ZO-1, Cx26 and Cx43, paper V
DISCUSSION
Preservation and the question of a representative material
The specific characteristics of the human spiral ganglion
Membrane specializations between the type 1 cells
Synapses on the neurons in the SG….
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Author: Tylstedt, Sven
Source: Umea University
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