Lab-on-chip (LOC) devices have miniaturized routine laboratory processes for automated, high-throughput chemical analysis. Separations of biomolecules, including protein and DNA, have been performed with high efficiencies in LOC devices, but the need for improved fluid flow control, i.e. pumping and valves, remains a significant challenge for next-generation systems. This dissertation explores the development of novel flow-control technology in polymer microfluidic networks for the realization of inexpensive, next-generation LOC devices. In the microchannels, electroosmotic flow (EOF) is used to electro-kinetically move the fluid with a longitudinal electric field…
Author: Sniadecki, Nathan
Source: University of Maryland
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