The intention of this report was to image and evaluate the needle behaviour at automated core biopsy, to research the clinical benefits of an alternative core biopsy approach employing a semiautomated gun in breast and axillary lesions, in addition to compare core biopsy with surgical specimens in cancerous breast lesions concerning histologic features and hormone receptor expression. In 2 experimental tests, using butter and silicon phantoms, respectively, the needle pass was imaged as well as the dynamic behavior examined. It had been revealed that the needle took a curved course in phantoms. It deviated to the same side as where the tip lay, and also the degree of the curvature increased with increasing firmness of the phantoms. Our experimental techniques can be employed for imaging of needle behavior and thus betterment of needle configuration. In 2 scientific studies, a semiautomated gun was utilized for big needle core biopsy of breast and axillary lesions in 2 series of 145 and 21 patients, respectively. The level of sensitivity of the technique for diagnosing malignancy was 87% (108/124), and in 37% (31/83) of cases the full length of the needle notch was filled up with sample. Absolutely no damage to the neurovascular structures of the axillary area was noticed…
Contents: Core Biopsy of Breast and Axillary Lesions
Introduction
Imaging Modalities
Ultrasound
Magnetic Resonance Imaging (MRI)
Fine Needle Aspiration Biopsy (FNAB)
Vacuum-assisted Biopsy (Mammotome)
Advanced Breast Biopsy Instrumentation (ABBI)
Core Biopsy
Advantages
Calcifications
Complications
Seeding
Learning Curve
Aims of the thesis
Material and methods
Study I
Study II
Study III
Study IV
Study V
Results
Study I
Study II
Study III
Study IV
Study V
Discussion
Remarks
Acknowledgments..
Source: Uppsala University Library
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