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Bone grafts and titanium implants are normally employed for surgical/prosthetic treatment of the atrophic edentulous maxilla. The aspects that have an impact on bone graft recovery and implant integration aren’t adequately understood. The purpose of this dissertation ended up being to assess
Ceramic attributes like biocompatibility and inertness have secured their utilization in biomedical prosthetics. The brittle character of ceramics governs their application in any design and fabrication approach. Current all-ceramic dental crowns have a recorded failing rate of around 3% annually. A study
The gastric pathogen Helicobacter pylori infects over fifty percent of people throughout the world. H. pylori have the ability to establish persistent infection, which could be life-long if not cured. To be able to set up this kind of infection, this pathogen
Anandamide (AEA) is surely an endogenous fatty acid that triggers the same cannabinoid receptors as tetrahydrocannabinol, the psychoactive substance in marijuana. In vivo, anandamide exerts numerous actions including effects upon inflammation and pain. Nevertheless, AEA has a brief time period of action
Plasmin, the main molecule of the plasminogen activator system, is actually a broad-spectrum serine protease. Plasmin is vital for the degradation of fibrin as well as other elements of the extracellular matrix (ECM) in a variety of physiological and pathological processes. The
Neuroblastoma is a childhood cancer which arises from neuroblasts in the peripheral nervous system. Neuroblastoma show substantial heterogeneity regarding location, responsiveness to treatment and prognosis. Due to the fact current therapy requires drugs with likelihood of severe negative effects in the growing
Psoriatic arthritis (PsA) is an inflammatory joint disease related to psoriasis. PsA has a heterogeneous structure, indicated by various manifestations like mild mono-oligoarthritis or very severe, erosive and damaging polyarthritis. Measurable inflammatory activity isn’t necessarily prominent. The aetiology is not known but
The assembly of ribosomal RNA (rRNA) and ribosomal proteins (r-proteins) into ribosomal subunits (30S and 50S) is actually a complex process. Transcription of rRNA needs antitermination proteins and the main transcripts are processed by ribonucleases. R-proteins and rRNAs are chemically altered, the
There is a considerable comorbidity between anxiety/depression and functional gastrointestinal syndromes, like irritable bowel syndrome (IBS) and functional dyspepsia. The pathophysiological link between emotions and the gut is not known. A model of an emotional motor system (EMS) that responds to interoceptive
Bacterial chromosomes are highly dynamic, continuously changing with respect to gene content and size via a number of processes, including deletions that result in gene loss. How deletions form and at what rates has been the focus of this thesis. In paper II we investigated how chromosomal location affects chromosomal deletion rates in S. typhimurium.