Clinical and Experimental Medicine Projects, Dissertation, Thesis, Working Papers, Research Papers, Experimental Medicine Examples, Resources and Information
Background: Atopic disease is an increasing problem. Eczema affects 10-20% of young children, and 33-37% of children with eczema are food allergic. Among other factors, nitric oxide (NO) is thought to play a role in eczema and food allergy. Following the atopic
Rheumatoid arthritis (RA) is a major cause of progressive joint damage and disability, and is associated with decline in quality of life, reduced ability to work and increased health care utilization. The economic consequences of the disease are substantial for the individuals
Voltage-gated ion channels are fundamental for electrical signaling in living cells. They are composed of four subunits, each holding six trans-membrane helices, S1-S6. Each subunit contains a voltage-sensor domain, S1-S4, and a pore domain, S5-S6. S4 contains several positively charged amino-acid residues
The aim of this thesis was to carry out an epidemiological study on mental health related issues in the Kurdish population of Iran. This part of Iran suffered directly during the Iran-Iraq war 1980-1988. Iran is an Islamic republic with strict adherence
Francisella tularensis, the causative agent of tularemia, is a potent pathogen in humans and other mammals. The ulceroglandular form of the disease is the most common expression in humans with a clinical picture characterized by a skin ulcer, enlarged regional lymph nodes
This thesis, comprising 5 separate studies, is concerned with fixation of prosthetic components in total hip arthroplasty. The results and conclusions of the studies fol-low;The initial stability of femoral revision components, the long cementless PCA stem and the Exeter standard stem cemented
Cancer is a process where the accumulation of several genetic alterations leads to a malignant transformation. Genetic alterations occur randomly at any location in the genome and will most often damage parts that are not of significant importance for the propagation of
Insulin is produced in the beta-cells in pancreatic islets of Langerhans. The insulin is needed for glucose to enter all cells and be used as a source of energy. An individual with diabetes suffers from insulin deficiency and hence an increased blood
The mevalonate pathway is an important biosynthetic pathway, found in all cells of virtually all known pro- as well as eukaryotic organisms. This thesis is an investigation into the use of two drugs, originally developed for different applications, but both affecting the
The supraspinatus tendon is an important structure of the rotator cuff. Subacromial impingement is a common reason for shoulder pain. Despite extensive scientific work in this field, the cause of impingement syndrome is still not fully understood. The general aim of the