Clinical/Experimental Medicine

Clinical and Experimental Medicine Projects, Dissertation, Thesis, Working Papers, Research Papers, Experimental Medicine Examples, Resources and Information

Metabolic aspects on diabetic nephropathy

Diabetic nephropathy (DN) is associated with morbidity and mortality due to cardiovascular disease and renal failure. This study focused on the impact of glycemic control on the development of DN and the metabolic consequences of DN. The euglycemic hyperinsulinemic clamp technique was used to assess insulin sensitivity and insulin clearance.

Health economic evaluation methods for decision-making in preventive dentistry

The aims of this thesis were to evaluate caries-preventive measures from a societal perspective, to demonstrate the use of resources in preventive dentistry, to develop and discuss techniques suitable for evaluating dental care costs and outcomes, and to test costs and consequences within a health economic decision model adapted to preventive dental care.

Metabolic disturbances in shift workers

An increased risk for coronary heart disease among shift workers is earlier shown in the epidemiological literature. The aim of this thesis has been to penetrate metabolic disturbances and obesity among shift workers compared to day workers, and to compare if there are differences in total mortality or cause specific mortality of coronary heart disease

Systemic sclerosis: vascular, pulmonary and immunological aspects

In systemic sclerosis (SSc), interstitial lung disease (ILD) and engagement of the vascular system lead to increased morbidity and mortality.The aim of this thesis was to elucidate, in a consecutively included cohort of SSc (limited and diffuse) patients (n = 33), the T cell cytokine profile driving the disease in ILD and to explore the role of matrix metalloproteinase 9 (MMP-9) and its inhibitor

Hormone replacement therapy: benefits and adverse effects

Several researches indicate that estrogen replacement therapy (ERT) is an efficient remedy for vasomotor symptoms, insomnia and vaginal dryness. Benefits are also shown on lipid patterns and on the incidence of osteoporotic fractures. As ERT estrogen replacement therapy enhances the risk of endometrial

Postnatal care – outcomes of various care options

Within high-income nations, clinic period of stay after having a normal delivery has steadily decreased correspondingly to period of stay in proper care of other patients. A brief stay gives a greater opportunity for autonomy as well as an increased sense of contribution, however it may involve great problems satisfying parental guidance as well as on the chance of preventing, acquiring, and treating neonatal health conditions.