The last decades less invasive monitoring and analytical tools have been developed for the evaluation of myocardial mechanics in clinical praxis. In critical care, these are longed-for complements to pulmonary artery catheter monitoring, additionally offering previously inaccessible information. This work is aimed, during fluid-replacement and oxygen therapy, to determine the physiological interface of ventricular and vascular mechanical properties, which result in the transfer of blood from the heart to appropriate circulatory beds. In prospective clinical studies we investigated previously cardiovascular healthy adults during hyperoxemia, and during preoperative acute normovolemic hemodilution or early fluid resuscitation of severe burn victims…
Contents
INTRODUCTION
Ventricular performance
Preload
Afterload
Acute preoperative normovolemic hemodilution
Hyperoxemia
Burn injuries
AIMS
METHODS
Pulmonary artery swan-ganz catheter
Transesophageal echocardiography
Doppler echocardiography and pulse tracing
Whole body impedance cardiography
Transpulmonary thermodilution with pulse contour analysis
Statistics
SUMMARY OF SUBJECTS AND RESULTS
Paper I
Paper II
Paper III
Paper IV
DISCUSSION
Hemodilution (I,III)
Hyperoxia (II)
Burn injuries (III, IV)
CONCLUSIONS
REFERENCES
ACKNOWLEDGEMENTS
APPENDIX WITH ORIGINAL PUBLICATIONS I-IV
Author: Bak, Zoltan
Source: Linköping University
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